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FLASH GENE
Symbol WDR12 contributors: mct/npt - updated : 03/12/2008
HGNC name WD repeat domain 12
HGNC id 14098
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven WD repats (TRP-ASP domain)
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be mediating protein-protein interactions
  • playing a crucial role for processing of the 32S precursor ribosomal RNA (rRNA) and cell proliferation
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • member of the Pes1-Bop1 complex (PeBoW complex, integrity of the PeBoW complex is required for ribosome biogenesis and cell proliferation in mammalian cells)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS