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FLASH GENE
Symbol TAF5L contributors: - updated : 15-11-2005
HGNC name TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
HGNC id 17304
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
six WD repeats
HOMOLOGY
Homologene
FAMILY WD-repeat TAF5 family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • may be playing an efficient role in acetylating histones in a nucleosomal context
  • may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation
    • CELLULAR PROCESS cell life, antiapoptosis
    nucleotide, transcription, initiation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the PCAF histone acetylase complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by PCNA
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene for diabete type 1 in russian patients
    Marker
    Therapy target
    ANIMAL & CELL MODELS