Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SH2D3A contributors: - updated : 25-07-2007
HGNC name SH2 domain containing 3A
HGNC id 16885
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an SH2 domain
  • an exchange factor-like domain binding both Ras GTPases and the scaffolding protein Cas
  • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to chimpanzee SH2D3A (99.7 pc)
    Homologene
    FAMILY
    CATEGORY adaptor , regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may play a role in JNK activation
  • acting as a SH3/SH2 adaptor
  • acting as a guanyl-nucleotide exchange factor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
  • JNK cascade
  • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with BCAR1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS