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FLASH GENE
Symbol PRIM1 contributors: - updated : 31-05-2006
HGNC name primase, polypeptide 1, 49kDa
HGNC id 9369
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,nucleus
basic FUNCTION synthesizing small RNA primers for the Okazaki fragments made during discontinuous DNA replication
CELLULAR PROCESS nucleotide, replication
nucleotide, transcription
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
  • smallest subunit of the pol alpha (POLA)/primare complex
  • heterodimer of a small subunit and a large subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   amplification    
    in osteosarcoma with CDK4, SAS, OS9
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS