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FLASH GENE
Symbol LZIC contributors: - updated : 09-01-2006
HGNC name leucine zipper and CTNNBIP1 domain containing
HGNC id 17497
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
leucine zipper domain
HOMOLOGY
interspecies ortholog to murine Lzic
ortholog to chicken lzic
homolog to dog LOC491440
Homologene
FAMILY
CATEGORY tumor suppressor
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • inhibiting the interactions between beta-catenin and TCF transcription factors
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in gastric cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS