basic FUNCTION
| glycine-N-acyltransferase protein conjugating glycine with acyl-CoA substrates in the mitochondria |
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having substantial capacity towards its preferred substrates, with indisputable therapeutic impact |
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is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA and in regulating glucose metabolism and energy metabolism |
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essential to glucose metabolism and energy metabolism, suggesting the gene dual role in both bone development and muscle growth |
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importance of GLYAT gene in co-regulation of bone phenotypes and body lean mass |
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essential to glucose metabolism and energy metabolism, suggesting the gene dual role in both bone development and muscle growth |
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is a phase II metabolic detoxification enzyme for exogenous (xenobiotic) and endogenous carboxylic acids |
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catalyzes the formation of hippurate (N-benzoylglycine) from the corresponding glycine and benzoyl-CoA |