Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC44A4 contributors: mct/npt - updated : 13-05-2009
HGNC name solute carrier family 44, member 4
HGNC id 13941
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • ten transmembrane domains
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to C.elegans F35C8.7
    ortholog to murine Ctl4
    intraspecies homolog to CTL1
    homolog to CTL2
    Homologene
    FAMILY
  • CTL (choline transporter-like) family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • acting as a choline transporters
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS facilitated diffusion transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
  • choline
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional fusion      
    CTL4/Neu1 fusion in sialidosis
    constitutional   deletion    
    in sialidosis
    Susceptibility to late onset Alzheimer disease (Webster 2009)
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS