motifs/domains
| a consensus RNA-binding domain (RNP-CS) |
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a N terminal SER, TYR, GLU, GLY rich domain, and transactivation domain, that serves as an essential transforming domain in the fusion oncoprotein created by chromosomal translocation in certain human chondrosarcomas |
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zinc finger domain |
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an RNA recognition motif (RRM) |
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C2-C2 finger motif in the central region |
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a C terminal RGG region, containing 19 repeats of degenerate DR(S) GG(G)-YGG sequence, and many Arg-Gly-Gly (RGG) repeats, responsible for the shuttling between the nucleus and the cytoplasm and the methylation of RGG repeats affects the subcellular localization of TAF15 (Jobert 2009) |