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FLASH GENE
Symbol PDGFD contributors: - updated : 13-08-2007
HGNC name platelet derived growth factor D
HGNC id 30620
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 23 amino acids signal peptide (2.6 kDa)
  • N terminal CUB domain
  • C terminal PDGF cystine knot growth factor domain
  • mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to chimpanzee PDGFD (100.00 pc)
    homolog to murine Pdgfd (85.14 pc)
    homolog to chicken PDGFD (81.15 pc)
    Homologene
    FAMILY
  • PDGF/VEGF growth factor superfamily
  • CATEGORY enzyme , signaling growth factor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION protease important for growth survival and fucntion in several types of connective tissue cells
    CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein PDGFR-beta, specifically
    cell & other
    REGULATION
    activated by limited proteolysis
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS