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FLASH GENE
Symbol NT5C3A contributors: mct/npt - updated : 07-07-2014
HGNC name 5'-nucleotidase, cytosolic IIIA
HGNC id 17820
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
  • pyrimidine 5'-nucleotidase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • catalyzing the dephosphorylation of pyrimidine nucleoside monophosphate
  • transferring phophate groups between pyrimidine monophosphates and varioux pririmidine nucleosides
  • is responsible for selective degradation of pyrimidine 5prime-monoribonucleotides during maturation of reticulocytes to erythrocytes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    pyrimidine metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Mg2+ dependent
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) P5N1D
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS