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FLASH GENE
Symbol ATP6V1G3 contributors: mct/npt - updated : 30-04-2010
HGNC name ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
HGNC id 18265
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an ATP catalytic site
  • HOMOLOGY
    Homologene
    FAMILY
  • V-ATPase G subunit family
  • CATEGORY enzyme , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • multisubunit enzyme mediating acidification of eukaryotic intracellular organelles
  • in the epididymis and vas deferens, the vacuolar H(+)ATPase (V-ATPase), located in the apical pole of narrow and clear cells, is required to establish an acidic luminal pH and also participates in the acidification of intracellular organelles (Pietrement 2006)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text proton transport
    PATHWAY
    metabolism
    signaling
    a component
  • component of vacuolar ATPase (V-ATPase)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS