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FLASH GENE
Symbol ZNF286A contributors: np - updated : 13-03-2003
HGNC name zinc finger protein 286A
HGNC id 13501
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one KRAB (Krüppel-associated box) at the N terminus
  • several tandemly arranged zinc finger motifs of the C2H2 type at the C terminus
  • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to Drosophila cg4936
    Homologene
    FAMILY
  • Krüppel family of C2H2 type zinc finger proteins
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • potential transcriptional rgulator
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional   deletion    
    in Smith-Magenis syndrome
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS