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FLASH GENE
Symbol SRRM1 contributors: npt/ - updated : 20-02-2013
HGNC name serine/arginine repetitive matrix 1
HGNC id 16638
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • PWI domain
  • multiple putative phosphorylation sites
  • SH3-binding motifs
  • HOMOLOGY
    interspecies homolog to murine Srrm1
    homolog to Drosophila cg3961
    homolog to C.elegans y65b4bl.5
    Homologene
    FAMILY
  • splicing factor SR family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    text nuclear matrix protein
    basic FUNCTION
  • required for splicing of specific pre-mRNAs
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the SRm 160/300 complex of nuclear matrix proteins
  • spliceosomal subunit
  • INTERACTION
    DNA
    RNA pre-mRNA dependent on RNU1A and stabilized by RNU2
    small molecule
    protein
  • SRRM2
  • SFRS5
  • SFRS4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS