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FLASH GENE
Symbol IPPK contributors: mct/npt - updated : 16-04-2010
HGNC name inositol 1,3,4,5,6-pentakisphosphate 2-kinase
HGNC id 14645
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a nuclear import signal
  • a peptide segment mediating the nuclear export of IPPK (Brehm 2007)
  • HOMOLOGY
    interspecies homolog to murine Ippk (91.4pc)
    homolog to rattus Ippk (92.2pc)
    Homologene
    FAMILY
  • IPK1 type 2 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,chromatin/chromosome
    intracellular,nucleus,nucleolus
    text preferentially localized in euchromatin and nucleoli, and co-localized with mRNA (Brehm 2007)
    basic FUNCTION
  • catalyzing the synthesis of inositol hexakisphosphate
  • plays a previously uncharacterized role in ciliary function (Sarmah 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism alcohol , carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS