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FLASH GENE
Symbol ARL6IP2 contributors: mct/npt - updated : 10-07-2008
HGNC name ADP-ribosylation factor-like 6 interacting protein 2
HGNC id 24047
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal domain
  • guanylate binding protein
  • ATP/GTP-binding site motif A (P-loop)
  • ring-type zinc finger
  • N- and C-termini facing the cytoplasm
  • conjugated HemoP
    HOMOLOGY
    interspecies ortholog to murine Arl6
    Homologene
    FAMILY
  • GBP family, atlastin family of GTPases
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,organelle,Golgi
    text localize prominently to ER membranes along microtubules
    basic FUNCTION
  • GTPase functioning prominently in both ER and Golgi morphogenesis, but they do not appear to be required generally for anterograde ER-to-Golgi trafficking
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • GTP
  • protein
  • binding to ARL6
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS