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FLASH GENE
Symbol SYTL5 contributors: mct - updated : 22-04-2011
HGNC name synaptotagmin-like 5
HGNC id 15589
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an intravesicular N terminal domain made of two conserved regions SHD1 and SHB2 fonctioning as protein interaction sites,a single transmembrane (TM) region,two protein kinase C-homologous repeats (Ca2+ binding domains C2) and a conserved WHXL motif in the C terminus
HOMOLOGY
Homologene
FAMILY
  • C type tandem C2 protein family (SLP family)
  • synaptotagmin family
  • CATEGORY regulatory , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    basic FUNCTION
  • involved in RAB27A dependent membrane trafficking in specific tissues
  • with SYT7, are positive regulators of chemotaxis (
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text vesicular trafficking
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein RAB27A (GTP bound form) binding
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS