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FLASH GENE
Symbol KTN1 contributors: - updated : 26-04-2006
HGNC name kinectin 1 (kinesin receptor)
HGNC id 6467
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • nuclear localization signal (NLS)
  • interspersed heptad repeats
  • HOMOLOGY
    Homologene
    FAMILY ser/thr protein kinase family, iKAPPAb kinase subfamily
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,nucleus
    basic FUNCTION
  • large integral ER membrane protein, phosphorylating inhibitors of NF-kappa-b thus leading to the dissociation of the inhibitor/NF-kappa-b complex and ultimately the degradation of the inhibitor
  • receptor for kinesin involved in kinesin-driven vesicle
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interact with mavs/IPS1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS