basic FUNCTION
| large integral ER membrane protein, phosphorylating inhibitors of NF-kappa-b thus leading to the dissociation of the inhibitor/NF-kappa-b complex and ultimately the degradation of the inhibitor |
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KTN1-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella |
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receptor for kinesin involved in kinesin-driven vesicle |
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KTN1 may play a functional role in the development of ADHD |
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promotes the occurrence and deterioration of HCC by mediating cell survival, migration, invasion, cell cycle activation, and apoptotic inhibition |
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KTN1 preferentially binds perinuclear polyglutamylated microtubules with long glutamate chains |