protein
| interacts with the C-termini of mu- and delta-opioid receptors |
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LMX1A is an activator of RGS4 and GRB10 and is responsible for the correct specification of rostral and medial mesodiencephalic dopamine (mdDA) neurons |
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both RAB5A activation and RAB11A inhibition decreased RGS4 function in a manner that is independent from their effects on the localization and function of the M1R/Gq signaling complex |
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RGS2 and RGS4 are new interacting partners that play key roles in G protein coupling to negatively regulate OPRK1 signaling |
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RGS4 in the paraventricular nucleus (PVN) regulates likely blood corticosteroid-related GABBR1 signaling during the acute stress response |
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crucial role of ATE1 in neural tube development is directly related to proper turn-over of the RGS4 protein, which participate in the oxygen-sensing mechanism in the cells |
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RGS4 is implicated in opioid dependent neuronal differentiation and neurite outgrowth via a "non-canonical" signaling pathway regulating STAT5B-directed responses |
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RGS4 controls secretion of von Willebrand factor (VWF) to the subendothelial matrix |
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SPARC promoted glucose-stimulated insulin secretion (GSIS) by inhibiting RGS4 in pancreatic beta cells |
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RGS4 appears essential for propionate/FFAR3 signaling attenuation in both cardiomyocytes and sympathetic neurons, leading to cardioprotection against inflammation/adverse remodeling and to sympatholysis, respectively |