protein
| binding directly to the C terminus of claudins |
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binding to occludin and alpha catenin |
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associating with F-actin (playing a role in several different steps of junction assembly) |
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bind to the C-terminus of OCLN |
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interaction with OCLN and PTPRJ specific (OCLN and TJP1 were dephosphorylated by PTPRJ but not the other phosphatases) |
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targets to gap junction edges independently of several known PDZ2-mediated interactions, including TJP1 homodimerization, heterodimerization with TJP2, and direct TJP1 binding to the C-terminal residues of GJA1) (H |
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by interacting with GJA1, plays a role in the down-regulation and decreased size of GJA1 gap junctions in congestive heart failure |
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interacting with KIRREL (tyrosine phosphorylation of KIRREL results in significantly increased KIRREL and TJP1 binding, suggesting a critical role for KIRREL tyrosine phosphorylation in reorganizing the KIRREL-TJP1 complex) |
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interacting with MYLK (MYLK activity is critical to TJP1, but not claudin-1, occludin, or actin) exchange at the tight junction) |
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interaction between TAZ and TJP1, TJP2, through TAZ C-terminal PDZ binding motif |
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TJP1 and the adherens junction protein PLEKHA7 as paracingulin-binding proteins |
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GJA8 requires an intact PDZ-binding motif and TJP1 for the formation of functional intercellular channels |
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interaction with UBN1 (N-terminal domains of the UBN1 and TJP1 proteins triggered a functional interaction inside the cell) |
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ARHGEF11 associates with tight junctions (TJs) by binding to TJP1, in polarized epithelial cells |
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KLF4 regulates blood-tumor barrier permeability via TJP1, OCLN and CLDN5 |
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direct interaction between VCL and TJP1, illustrating how VCL plays a crucial role in stabilizing gap junctions and myocyte integrity |
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CALCR interacts with zonula occludens 1 (TJP1) through PDZ interaction to destabilize tight junctions and increase invasion of prostate cancers (PCs) cells |