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FLASH GENE
Symbol LACRT contributors: npt/ - updated : 29-05-2006
HGNC name lacritin
HGNC id 16430
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six putative O-glycosylation sites
  • an N-glycosylation site near the C terminus
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY secretory , signaling
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,cytosolic,granule
    text secretory granules
    basic FUNCTION
  • augmenting lacrimal acinar cell secretion
  • promoting ductal cells proliferation
  • stimulating signaling through tyrosine phosphorylation and release of Ca2+
  • playing a role in the function of the lacrimal gland-corneal axis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • collagen IV
  • laminin-1
  • entactin/nidogen-1
  • fibronectin
  • vitronectin
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS