basic FUNCTION
| modifying proteins and lipids in the secretory pathway |
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golgi targeting information |
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Golgi protein containing stem domain Golgi targeting determinants, cycle to the cell surface and back along the late endosome independent TGN38/46 pathway (Puri 2002) |
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undergoes endosome-to-Golgi retrieval using the late endosome-bypass pathway in nonpolarized cells, cycles via the basolateral membrane in polarized MDCK cells (Puthenveedu 2003) |
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integral membrane protein retrieved via the bypass pathway from endosomes to its steady-state location in the cis-Golgi (Natarajan 2004) |
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required for efficient exit of Shiga toxin B-fragment from endosomes en route to the Golgi apparatus (Natarajan 2004) |
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cis Golgi protein, representative of proteins cycling between the Golgi apparatus and endosomes in a pH-sensitive manner (Starr 2007) |