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FLASH GENE
Symbol CSRNP1 contributors: SGE/npt - updated : 03-12-2009
HGNC name cysteine-serine-rich nuclear protein 1
HGNC id 14300
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to rattus Csrnp1 (73.9pc)
homolog to murine Csrnp1 (75.3pc)
Homologene
FAMILY
  • AXUD1 family (cysteine- serine-rich nuclear proteins family)
  • CATEGORY regulatory , tumor suppressor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • having transcriptional activator activity
  • may play a role in apoptosismay be a tumor suppressor
  • CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding to the consensus sequence 5'-AGAGTG-3'
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    inhibited by elevated levels of axin
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in lung, kidney, liver and colon cancers
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS