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FLASH GENE
Symbol GNG8 contributors: KTN/npt - updated : 09/09/2008
HGNC name guanine nucleotide binding protein (G protein), gamma 8
HGNC id 19664
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated LipoP
mono polymer heteromer , trimer
HOMOLOGY
interspecies homolog to dog GNG8 (98.6 pc)
homolog to rattus Gng8 (98.6 pc)
homolog to murine Gng8 (98.6 pc)
Homologene
FAMILY G protein gamma family
CATEGORY signaling , receptor membrane G
SUBCELLULAR LOCALIZATION extracellular
    plasma membrane
text
  • lipid-anchor
  • cytoplasmic side
  • basic FUNCTION
  • involved as a modulator or transducer in various transmembrane signaling systems
  • required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal , signal transduction
  • hormone-mediated signaling
  • a component
  • prenylation
  • heterotrimeric G-protein complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS