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FLASH GENE
Symbol DDX10 contributors: - updated : 21-04-2006
HGNC name DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
HGNC id 2735
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
DEAD/H box (Asp-Glu-Ala-Asp/His), helicase C terminal domain
HOMOLOGY
Homologene
FAMILY DEAD/H box protein 10 family
CATEGORY enzyme , RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION RNA helicase with RNA dependent ATPase activity, may be involved in ribosome assembly
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral fusion      
with NUP98 in de novo or therapy related myeloid malignancies with inv 11(p15-q22)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS