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FLASH GENE
Symbol ACOT8 contributors: mct/npt - updated : 17-06-2008
HGNC name acyl-CoA thioesterase 8
HGNC id 15919
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Acot8
Homologene
FAMILY
  • C/M/P thioester hydrolase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • involved in fatty acid oxydation
  • acyl-CoA thioesterase activity showing a preference for medium-length fatty acyl-CoAs
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with HIV-NEF
  • cell & other
    REGULATION
    Other regulated by peroxisome proliferator, via the peroxisome proliferator-activated receptors (PPARs)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS