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FLASH GENE
Symbol ZNF330 contributors: - updated : 14-03-2003
HGNC name zinc finger protein 330
HGNC id 15462
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal localization signal (NLS)
  • nine cysteine X-X cysteine motifs of zinc finger type
  • a C terminal poly-acidic region
  • conjugated MetalloP
    HOMOLOGY
    interspecies ortholog to highly conserved genes from C.elegans to human
    Homologene
    FAMILY NOA36 family
    CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,centromere
    intracellular,nucleus,nucleolus
    text RNA-dependent nucleolar localization in interphase associated with centromeres at mitosis,and midbodies at cytokinesis
    basic FUNCTION cell-cycle control and transcriptional regulation
    CELLULAR PROCESS cell cycle
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    autoimmune antigen in a patient suffering from rhumatoid arthritis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS