Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HRH3 contributors: mct/npt - updated : 25-06-2008
HGNC name histamine receptor H3
HGNC id 5184
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane domains (7TM)
  • HOMOLOGY
    Homologene
    FAMILY
  • G protein-coupled receptors family 1
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • regulating the neurotransmitter release
  • increasing voltage dependent calcium current in smooth muscles (and innervation of blood vessels)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interazcting wth CLIC4 (binding to the C-terminus of HRH3, CLIC4 plays a critical role in regulation of the receptor cell surface expression)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS