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FLASH GENE
Symbol SLC38A4 contributors: np/ - updated : 05-07-2007
HGNC name solute carrier family 38, member 4
HGNC id 14679
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • ten transmembrane domains which putatively place both the amino and C terminus in the cythoplasm
  • HOMOLOGY
    interspecies ortholog to murine mNAT
    ortholog to rattus ata3
    Homologene
    FAMILY
  • amino acid transporters
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • amino acid uptake likely playing an important role in arginine uptake by liver
  • contribution to placental system A activity is relatively high during first trimester and decreases towards term
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text neutral amino acidNa(+)np; H dependent; catronic amino acids (Na+) independent
    PATHWAY
    metabolism aminoacid
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS