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FLASH GENE
Symbol GDF10 contributors: - updated : 11-04-2006
HGNC name growth differentiation factor 10
HGNC id 4215
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
TGF-beta like domain
mono polymer homomer , heteromer , dimer
isoforms Precursor cleaved at a consensus Arg-X-X-Arg to yield a C terminus mature dimer
HOMOLOGY
interspecies homolog to Drosophila decapentaplegic-Vg,DVR family
Homologene
FAMILY
  • TGFB superfamily, BMP family
  • CATEGORY signaling growth factor
    SUBCELLULAR LOCALIZATION extracellular
    text secreted
    basic FUNCTION regulator of cell growth
    CELLULAR PROCESS cell life, differentiation
    cell life, proliferation/growth
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS development
    text skeletal morphogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by cleaved by subtilisin like convertases
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS