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FLASH GENE
Symbol GNB1L contributors: mct - updated : 25-03-2008
HGNC name guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HGNC id 4397
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal six putative WD40 repeat (44 to 60AA containing GLY-HIS)
  • C terminal WD (TRP-ASP) dipeptide and a conserved core sequence
  • HOMOLOGY
    interspecies homolog to murine gub1l
    Homologene
    FAMILY WD40 repeat family
    CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to schizophrenia
    Variant & Polymorphism SNP increasing the risk of schizophrenia
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS