basic FUNCTION
| involved in growth control and terminal differentiation in cancer cells, negative regulator of melanoma progression |
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functions potentially during an inflammatory response in the skin by inhibiting the proliferation and migration of keratinocytes |
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specifically inhibits cancer cell growth through the induction of cell cycle arrest and apoptosis |
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suppressed mRNA expression of vascular endothelial growth factor and platelet-derived growth factor and subsequently decreased the level of cell migration in response to H(2)O(2) |
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suppress tumor progression in a variety of human cancers |
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cytokine with potent antitumour and tumour-suppressive activity which functions through its receptor (IL22R) |
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plays a profound role in suppressing tumour lymphangiogenesis, thereby, reducing the likelihood of cancer metastasis via the lymphatic route |
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IL24 and IL19 are involved in host defence against bacteria and fungi, tissue remodelling and wound healing |