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FLASH GENE
Symbol IMMP2L contributors: mct - updated : 06-09-2011
HGNC name IMP2 inner mitochondrial membrane protease-like (S. cerevisiae)
HGNC id 14598
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N terminal transmembrane domain
  • a signal peptidase 1 domain (anchored in the cytoplasmic membrane, removing the signal peptides from secretory proteins)
    • HOMOLOGY
    interspecies homolog to yeast imp2
    ortholog to murine Immp2l
    ortholog to chicken immp2l
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • acting as a serine-type peptidase
  • involved in folliculogenesis or male fertility
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) GTS7
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    dysruption of the gene in 1 case of Gilles de la Tourette syndrome
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS