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FLASH GENE
Symbol CHPT1 contributors: mct/npt - updated : 07/11/2008
HGNC name choline phosphotransferase 1
HGNC id 17852
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a CDP-alcohol phosphotranferase motif with the final two Asp residues
  • HOMOLOGY
    intraspecies paralog to CEPT1
    Homologene
    FAMILY
  • CDP-alcohol phosphatidyltransferase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION
  • catalyzing the transfer of phosphocholine from diphosphocholine (CDP) to diacylglycerol (DAG) with the release of CMP and formation of phosphatidylcholin (CP)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in cancerous breast epithelial cell line when compared to that of normal non-tumorigenic breast epithelial cell line
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS