Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TRAT1 contributors: npt - updated : 01-07-2002
HGNC name T cell receptor associated transmembrane adaptor 1
HGNC id 30698
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a short extracellular domain
  • a transmembrane segment (TM1)
  • a large cytoplasmic tail containing several tyrosine based signaling motifs that could be involved in SH2 mediated protein-protein interactions
  • conjugated PhosphoP
    mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY adaptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • likely involved in targeting of intracellular signaling proteins to the plasma membrane after triggering of TCR and phosphorylation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • associating and comodulating with the TCR-CD3-zeta complex
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS