Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PLCD3 contributors: - updated : 28-03-2006
HGNC name phospholipase C, delta 3
HGNC id 9061
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
c2 domain.
  • two EF-hand domains
  • a PH domain
  • a PI-PLC X-box domain
  • a PI-PLC Y-box domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • phospholipase C, delta 3, phosphatidylinositol specific
  • catalyzing the hydrolysis of phosphatidylinositol 4,5 biphosphate to generate diacylglycerol and inositol 1,4,5 triphosphate
  • mediating a wide variety of cellular stimuli
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binds 3 calcium ions per subunit( two of the calcium ions are bound to the C2 domain)
    protein
    cell & other
    REGULATION
    inhibited by by cAMP and calcium
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS