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FLASH GENE
Symbol ZNF85 contributors: - updated : 25-03-2006
HGNC name zinc finger protein 85 (HPF4, HTF1)
HGNC id 13160
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 16 C2H2 zinc finger domain
  • one KRAB box domain
  • multiple nuclear localization signals (NLS)
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • zinc finger protein family, C2H2 Kruppel type)
  • KRAB subfamily
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION transcriptional repressor
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in seminomas
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS