basic FUNCTION
| structural protein, actin, alpha 2 |
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major constituent of the contractile apparatus, involved in cell motility, structure and integrity |
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playing a role in adult aortic endothelium and possible association with progression of atherosclerosis (Azuma 2009) |
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most abundant protein in the smooth muscle cells that populate the affected arteries and participates in cell proliferation, migration, and force transduction |
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specifically mediates myoepithelial cell contraction during lactation and this actin isoform therefore exhibits functional specificity |