basic FUNCTION
| participating in blood cell-specific responses to interferons |
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may be acting as a transcriptional activator/repressor in the myeloid lineage |
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MNDA and related proteins appear to modulate the activity of transcription factors and in some cases have a role in mediating cell death |
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has likely a role regulating programmed cell death in myeloid progenitor cells, and its down-regulation in myelodysplastic syndromes (MDS) is related to granulocyte-macrophage progenitor cell sensitivity to TNFSF10-induced programmed cell death |
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role of FGF4 and MNDA in pluripotent cell responses to genotoxicity |
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is a nuclear protein that labels myelomonocytic cells as well as B lymphocytes that localize to the marginal zone areas of splenic white pulp |