Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | LAMC2 | contributors: mct/npt - updated : 21-09-2015 |
HGNC name | laminin, gamma 2 |
HGNC id | 6493 |
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PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
conjugated | GlycoP |
mono polymer | heteromer , trimer |
isoforms | Precursor | a 1172 amino acids mature peptide (128.8 kDa) |
HOMOLOGY |
interspecies | homolog to rattus Lamc2 (84.96 pc) |
homolog to murine Lamc2 (83.91 pc) |
Homologene |
FAMILY |
CATEGORY | adhesion , structural protein |
SUBCELLULAR LOCALIZATION | extracellular |
text | basement membrane |
CELLULAR PROCESS | cell life, proliferation/growth |
cell communication |
PHYSIOLOGICAL PROCESS | development |
PATHWAY |
metabolism |
signaling | signal transduction |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
activated by | cleaved by BMP1,facilitating basement membrane assembly |
Other | its expression was regulated by histone methylation as well as DNA methylation |
ASSOCIATED DISORDERS |
corresponding disease(s) | EBJ1A , EBJ2A |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |