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FLASH GENE
Symbol PTDSS2 contributors: KTN/npt - updated : 30/10/2008
HGNC name phosphatidylserine synthase 2
HGNC id 15463
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies homolog to dog PTDSS2 (90.7 pc)
homolog to chimpanzee PTDSS2 (97.5 pc)
homolog to rattus Ptdss2 (91.7 pc)
homolog to murine Ptdss2 (92.1 pc)
homolog to chicken PTDSS2 (87.5 pc)
Homologene
FAMILY
  • phosphatidyl serine synthase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    text
  • mitochondria-associated membrane
  • multi-pass membrane protein
  • basic FUNCTION
  • catalyzing a base-exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine
  • acting as a CDP-diacylglycerol-serine O-phosphatidyltransferase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism other
    signaling
  • phospholipid metabolism
  • phosphatidylserine biosynthesis
  • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    inhibited by excess phosphatidylserine
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS