basic FUNCTION
| endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' |
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termini of tRNAs |
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RNase Z(L) that is the enzyme involved in both, nuclear and mitochondrial tRNA 3 prime end maturation |
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functions as a tRNase Z in human mitochondria, suggesting that mt-tRNase Z preferentially cleaves molecules already processed by the proteinaceous mtRNase P |
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having an important transcriptional scaffold function in TGF-beta/Smad signaling mediated growth arrest |
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encodes a long form of RNase Z |
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role of ELAC2 in mt-tRNA processing |