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FLASH GENE
Symbol SNX15 contributors: - updated : 24-10-2005
HGNC name sorting nexin 15
HGNC id 14978
PROTEIN
PHYSICAL PROPERTIES globular
STRUCTURE
motifs/domains
  • N terminal PHOX homology domain
  • a C terminal ESP domain
  • a MIT domain
  • mono polymer homomer , heteromer , polymer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,organelle,endosome
    basic FUNCTION playing a role in the normal trafficking of protein from the plasma membrane to recycling endosome or the trans-Golgi network
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text receptor trafficking
    PATHWAY
    metabolism
    signaling
    a component homo and hetero oligomers with SNX1, SNX2, SNX3, SNX4
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • platelets derived growth factor receptors (PGDFRA, PDGFRB)
  • interacting with ESCRT-III proteins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS