SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,membrane
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| intracellular,cytoplasm,organelle,Golgi
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| intracellular,cytoplasm,organelle,endosome
|
| intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
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text
| filamentous pattern through cytoplasm |
basic FUNCTION
| playing a role in tumorigenesis (brain cancer) and drug resistance of the SNB-78 cell linee at least |
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multifunctional protein, which processes ubiquitin-conjugating activity, as a major regulator of abscission |
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coordinates multiple steps required for abscission and ubiquitylation may be a crucial trigger |
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antagonizes both the precursor and mature forms of Smac and caspase-9 |
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having has an essential function in preventing DIABLO-induced apoptosis |
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is a target for glucocorticoid hormones (GHs) in the neural progenitor cells (NPCs), and controls cell division of NPCs and possibly of other stem cells |
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BIRC6 and USP8 are two hitherto uncharacterized critical DNA damage response (DDR) regulators |