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FLASH GENE
Symbol OMD contributors: - updated : 24-01-2007
HGNC name osteomodulin
HGNC id 8134
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 12 LRR (leucine-rich) repeats, flanked by cysteine-rich regions
  • HOMOLOGY
    Homologene
    FAMILY small leucine-rich proteoglycan (SLRP) family, class II subfamily
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION extracellular
    text dental pulp
    basic FUNCTION
  • potentially involved in biomineralization process
  • having a function in binding of osteoblasts via the alpha(V)beta(3)- integrin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds keratan sulfate chains
    cell & other
    REGULATION
    activated by TGF beta 1 in pulpal fibroblasts and in early secretory and mature odontoblasts
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS