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FLASH GENE
Symbol FXYD2 contributors: npt/ - updated : 09-03-2006
HGNC name FXYD domain containing ion transport regulator 2
HGNC id 4026
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 35 AA signature with the PFXYD motif at the beginning
  • a cytoplasmic positively charged C terminus
  • secondary structure alpha (catalytic) beta and gamma subunit
    conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to murine Fxyd2
    Homologene
    FAMILY
  • FXYD2 family
  • CATEGORY regulatory , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    text basolateral membrane
    basic FUNCTION
  • regulatory subunit of Na,K-ATPase in the kidney, pancreas, liver
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) HOMG2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS