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FLASH GENE
Symbol AASS contributors: - updated : 05-05-2006
HGNC name aminoadipate-semialdehyde synthase
HGNC id 17366
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
interspecies ortholog to yeast S.cerevisiae LYS1/LYS9
ortholog to murine Aass
Homologene
FAMILY
  • AlaDH/PNT family in the N-terminal section
  • saccharopine dehydrogenase family in the C-terminal section
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION . bifunctional enzyme catalyzing the first two steps in the mammalian lysine degradation pathway
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism aminoacid
    signaling
    lysine catabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by starvation
    ASSOCIATED DISORDERS
    corresponding disease(s) AASS , SCDD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS