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FLASH GENE
Symbol SULT1B1 contributors: mct - updated : 13-12-2017
HGNC name sulfotransferase family, cytosolic, 1B, member 1
HGNC id 17845
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
interspecies homolog to murine Sult1d1
intraspecies homolog to SULT1
Homologene
FAMILY sulfotransferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,Golgi
intracellular,cytoplasm,cytosolic
text
  • detected in the kidney exclusively in the Golgi apparatus of the podocyte
  • basic FUNCTION
  • catalyzing the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds
  • functional role of ST1B subfamily of sulfotransferases (STs) in xanthurenic acid sulfate formation in the body
  • may be involved in the sulfonylation of podocyte protein podocalyxin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS