Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KCNS1 contributors: mct - updated : 24-06-2014
HGNC name potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
HGNC id 6300
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • transmembrane protein with six putative membrane-spanning domains
  • an hydrophobic pore including the P domain with the K+ channel signature, flanked by TM domains 5 and 6, sensitive to changes in membrane potential
  • mono polymer heteromer , polymer
    HOMOLOGY
    interspecies homolog to murine Kcns1
    Homologene
    FAMILY
  • potassium channel family
  • S subfamily
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acting as regulatory a-subunit of Shab family voltage-gated K channel
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • modulator of KCNB1
  • cell & other
    REGULATION
    activated by BMP2 that significantly (>2-fold) upregulated mRNA expression of KCNS1
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS