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FLASH GENE
Symbol RAB3IL1 contributors: mct - updated : 02-02-2017
HGNC name RAB3A interacting protein (rabin3)-like 1
HGNC id 9780
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • SEC2 family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • GTPase activity
  • regulates depolarization-induced release of dopamine from PC12 cells
  • RAB3IL1 and its binding partner UNC13B, and the subsequent gating of vesicle fusion by activation of the Ca2+ channels, are implicated in the docking of vesicles at the transmitter release site, a process of neurosecretion
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • is a dual RAB-binding protein that could potentially link RAB3A and RAB11A/RAB11B and/or RAB8A/RAB8B and RAB11-mediated intracellular trafficking processes
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS