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FLASH GENE
Symbol ZKSCAN5 contributors: np - updated : 03-03-2003
HGNC name zinc finger with KRAB and SCAN domains 5
HGNC id 12867
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  highly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text widely with strongest expression in testis
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • SCAN box leucine-rich mediating self association and oligomerization and a KRAB Kruppel associated box at the N terminus
  • twelve highly conserved zinc finger motifs at the C terminus
  • conjugated MetalloP
    HOMOLOGY
    interspecies ortholog to murine Zfp95
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • transcriptional repressor
  • maybe involved in spermatogenesis and developmental processes
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS